Proteins and biotechnologies

Coordinators

Loïc Rajjou, Julia Zinsmeister

Goals

Assessment in this unit is designed to evaluate a combination of scientific knowledge, analytical ability, and applied problem-solving skills. The written report assesses students’ capacity to synthesise scientific literature, critically appraise biotechnological approaches, and contextualise them within ethical and regulatory frameworks. The oral examination evaluates students’ ability to communicate complex scientific concepts clearly, defend arguments, and demonstrate integrative understanding across molecular, physiological, and technological dimensions. The written examination in the second session tests comprehensive knowledge of alternative protein sources, mastery of genetic and protein engineering techniques, and the ability to apply theoretical concepts to novel or emerging biotechnological challenges.

Content

The programme first introduces the major families of alternative proteins (plant-based, insect-derived, microbial), their functional properties, and their prospects for use in food systems. It then addresses the biotechnological approaches involved, ranging from conventional techniques such as mutagenesis, transgenesis and cisgenesis, to new genome-editing technologies, as well as the contributions of protein engineering, synthetic biology, and systems biology. Cross-cutting themes, including protein separation, industrial transformation processes, and metabolic pathway engineering, are also explored. Ethical, societal, and regulatory aspects of applying biotechnology to food production are considered throughout. The course is complemented by a research and development centre visit, allowing students to directly link theoretical knowledge with industrial applications.

Format

The unit is structured around 14h of lectures, 16h of tutorials, and 6h dedicated to a supervised project, in addition to the R&D centre visit. Lectures provide the conceptual foundations and highlight recent advances in the field, while tutorials encourage active learning through case studies, critical discussions, and problem-solving exercises. The supervised project allows students to work independently on an applied problem, thereby integrating theoretical knowledge with creativity and analytical skills. Assessment in the first session consists of coursework (written dossier, 30%) and an oral examination (70%), while the second session consists of a final written examination (100%). This structure supports progressive, interactive learning and fosters analytical, critical, and applied competences required to address the challenges of protein biotechnology.

Language : English

Elective TU

ECTS : 4

Lectures : 14 ;  Directed Study : 16; Tutored Project : 6